| Methodology Report #12: Outpatient Prescription Drugs: Data Collection and Editing in the 1996 MEPS (HC-010A) by John F. Moeller, Ph.D., and Marie N. Stagnitti, M.P.A., Agency for Healthcare Research and Quality; Eileen Horan and Pat Ward, Ph.D., Westat, Inc.; and Nancy Kieffer and Ed Hock, Social and Scientific Systems, Inc.
 
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          Medical Expenditure Panel Survey (MEPS).
 
 
 
 Abstract
 The Medical Expenditure Panel Survey (MEPS) is the third in a series of nationally representative surveys of medical care use and expenditures sponsored by the Agency for Healthcare Research and Quality (AHRQ). For the first time in a national expenditure survey, the 1996 MEPS included a detailed collection of information on prescription medicines obtained from pharmacy providers frequented by household sampled persons. The information was collected by means of a linked survey of pharmacy providers. This report describes the procedures adopted to collect and edit these prescription drug data for public release. It includes efforts made to retrieve complete and/or partially missing pharmacy data, the editing techniques used to fill in remaining missing data in the pharmacy database, and the matching/imputation procedure that linked every prescription drug mentioned by the respondent in the MEPS Household Component to a specific prescription drug from the Pharmacy Component (part of the Medical Provider Component). 
 
 
 
 
 Introduction           This report describes the procedures adopted to          collect and edit the 1996 Medical Expenditure Panel Survey (MEPS)          prescription drug data for public release (MEPS public use file          HC-010A). For the first time in a national expenditure survey, the 1996          MEPS included a detailed collection of information on prescription          medicines obtained from pharmacy providers frequented by household          sampled persons. The information was collected by means of a linked          survey of pharmacy providers. Because of nonresponse to the linked survey, these          prescription data were not available for every sampled person in MEPS          and were not necessarily complete for those persons for whom the          Pharmacy Component (PC) survey data were collected. Hence, this report          discusses the data collection efforts made to retrieve complete and/or          partially missing pharmacy data, the editing techniques used to fill in          remaining missing data in the pharmacy database, and the          matching/imputation procedure that linked every prescription drug          mentioned by the respondent in the MEPS Household Component (HC) to a          specific prescription drug from the PC. The abbreviations used in this          report are listed in Appendix A. The MEPS prescription drug use and expenditure          data comprise a critical component of health expenditures collected in          the survey. Recently, there has been considerable policy interest in          developing a prescription drug benefit for the Medicare population. In          addition, the rising cost of prescription drugs has been singled out as          a leading contributor to the escalating premiums for plans covering the          non-Medicare population. Apart from coverage issues, it is critical to          have accurate, detailed information on drug therapies in order to          analyze alternative treatment regimens for disease and to investigate          the potential for adverse drug interactions in treating chronic          illnesses. Previous household health expenditure surveys have          been criticized for underestimating utilization and  expenditures          on prescribed medicines because of respondent underreporting of          prescription data. The potential for this problem is understandable when          considering the length of the recall period in the expenditure surveys,          the burden placed on the respondent to report details of numerous          medication purchases for household members, the irregular frequency with          which prescriptions are purchased for treating acute health conditions          during a survey period, and the complexity of reimbursement mechanisms          for prescription medicines. The general approach used in MEPS to address the          underreporting issue was to relieve the household of the burden of          reporting detailed financial information for every prescription purchase          during each round of the survey. Instead, computerized printouts from          respondents pharmacy providers that contained such information were          used when they were available. When computerized printouts were          unavailable from a pharmacy provider, completed written data forms were          secured, when possible. These printouts or forms also provided detailed          information about the pharmacology of the prescription summarized by the          National Drug Code (NDC). Heretofore, this information had not been          available from household health expenditure surveys. In addition,          efforts were made to improve the reporting accuracy of prescription          utilization by asking the household respondent about medications          prescribed in conjunction with other medical events, such as hospital          stays, emergency room visits, and doctor visits. This information was          gathered at the same time during the survey that the respondent was          queried about other nonprescription events. The challenge was to match prescription mentions          by the household to the prescription purchases on their computerized          printouts. When computerized printouts were not available for MEPS          households from their pharmacy providers, detailed information on          specific prescription purchases by participating individuals in the PC          had to be imputed to the drug mentions of the HC nonparticipating          individuals. (HC nonparticipating  individuals are respondents          whose pharmacy providers were not contacted because permission forms          were not signed or whose pharmacy providers were contacted but did not          provide information about the individuals prescriptions.) Once the          pricing and payment data from the PC were either matched or imputed to          all of the household prescription mentions, the prescription          expenditures and payments could be "rolled up" from the event          or purchase level to the person level for estimating national          prescription expenditures and payment sources for the entire U.S.          civilian noninstitutionalized population in 1996.  Return to Top
           Data Collection   Household Component  Prescription drug data were collected in the MEPS          HC questionnaire and in the linked MEPS PC. During each round of the          MEPS HC, all respondents were asked to supply the name(s) of any          prescribed medication that they or their family members purchased or          otherwise obtained during that round. Respondents were first given an opportunity to          mention prescribed drugs when they were surveyed about other          (nonprescription) health service events. They were given a last          opportunity to mention prescribed medicines during the prescribed          medicines section of the HC. The order in which health care events are          described in the HC is simply an artifact of the design of the HC.          During each round of the HC, detailed information was obtained on          various types of health care service events, including prescribed          medicines. When respondents provided information on a health care event          that was not a prescribed medicine (e.g., an emergency room visit), they          were asked to supply information describing the health care event          itself, as well as the names of any medications that were prescribed          during that event. In addition, prescribed medicine mentions could be          added when respondents went through the prescribed medicines section of          the household questionnaire. These are the ways in which a respondent          "created" (possible during Rounds 1-5) and/or          "selected" (possible  during Rounds 2-5) prescribed          medicine mentions for their prescribed medicines roster.          "Created" means that the respondent had not mentioned the          prescribed medicine in any previous round of the survey, while          "selected" means that the respondent had mentioned the          prescribed medicine during a previous round. This roster served as a          "base" prescribed medicines roster for that respondent          throughout all of his or her rounds in MEPS. In each round, respondents          had a final opportunity to add any additional medication names to their          roster of prescribed medicines in the prescription drug section of the          MEPS HC. The following information was collected in the          prescribed medicines section of the questionnaire for each medication          listed on the roster in each round of MEPS: whether any free samples of          the medication were obtained; the name(s) of any health problem(s) for          which the medication was prescribed; the number of times the          prescription drug was obtained or purchased; the year, month, and day on          which the person first used the medication; and a list of the names,          addresses, and types of pharmacies that filled the households          prescriptions. In addition, all the HC respondents were asked if they          send in claim forms for their prescriptions (this type of person is          referred to as a self-filer, or SF) or if their pharmacy providers do          this automatically for them at the point of purchase (this type of          person is designated as a non-self-filer, or NSF). Uninsured persons          were treated in the same manner as NSFs.1 The uninsured were not asked          charge and payment questions during the HC. Only SFs were asked for          charge and payment information about their prescription purchases on the          household questionnaire. Payments by private third parties for SF          prescription purchases would not be available from the pharmacy          provider. When diabetic supplies and equipment (such as          syringes and insulin) were mentioned in the section of the MEPS HC on          other medical expenses, the interviewer was directed to collect          information on these items in the prescription medicines section. To the          extent that these items are purchased without prescription, they          represent a nonprescription addition to the MEPS prescription drug          expenditure and utilization data. 
  1 The uninsured are included in the NSF          group throughout this report. Return to Top Pharmacy Component  The PC was designed as a mail survey of the          pharmacy providers identified by household respondents during the series          of MEPS interviews covering calendar year 1996. (See Appendix B for a          facsimile of the mailed PC survey booklet.) During the last of these          interviews, the household respondents were asked to sign permission          forms (Appendix C) authorizing the project to contact their pharmacies          and authorizing the pharmacies to release a respondents pharmacy          records. Only those pharmacies for which a household respondent signed          this permission form were included in the linked followback survey. The data collection protocol consisted of an          initial mailing to all of the nominated pharmacies for which one or more          permission forms had been obtained, a second mailing to nonrespondents,          and followup telephone prompting of pharmacies that did not respond to          the mailings. The initial mailing (Appendix B) was designed in the form          of a printed booklet containing an introductory letter from the Agency          for Healthcare Research and Quality (AHRQ) and the National Center for          Health Statistics (NCHS), a brief description of MEPS and the PC,          answers to frequently asked questions about the study, and an          explanation of the data items being requested. A computer printout          listing the persons for whom the pharmacy was being asked to provide          information and copies of the signed permission forms were inserted          inside the back cover of the booklet. The data request offered          pharmacies two main options for responding. If available, pharmacies          were invited to send computerized printouts of the data for the          identified patients. This was seen as a response option imposing minimal          burden on pharmacies, many of which routinely provide such printed          listings to customers who request them. Alternatively, pharmacies could          fill in the requested information on data forms, which were inserted in          the booklet along with the patient list and permission forms. The pharmacies were asked to provide information          about each prescription filled or refilled for the named patients during          calendar year 1996. For each medication, they were asked to provide: 
             The date the prescription was filled or              refilled. The NDC. The medication name (generic or brand). The strength of the medicine. The quantity dispensed. The total charge. The sources of payment. The amount of payment made by each              source. The initial mailings were directed to the          individual retail pharmacies or other specific locations identified by          the household respondents as the places from which household members had          obtained their prescriptions. Although it was expected that some          pharmacy chains might require corporate permission before allowing their          individual locations to participate and that some would prefer to          provide information from regional or corporate resources, the plan was          to make the first contacts at the individual locations, working up the          corporate ladder only after being referred there by the local          pharmacies. "Chain" codes were assigned to the individual          pharmacies, creating a mechanism for associating local establishments          with a shared corporate parent. The final round of household interviews through          which the pharmacy sample was identified ended in July 1997. After a          period of sample preparation, the first waves of mailings were released          in September 1997. The bulk of the mailings, grouped in nine waves          defined by groups of States, was completed by the end of October 1997; a          final wave of cases that had required problem resolution was released in          January 1998. The followup mailings began in late September 1997 and          continued into December 1997. Calls to prompt nonresponding pharmacies          began in mid-December 1997. The response to the first wave of mailings was          promising, with replies received from as many as 40-50 percent of the          pharmacies. The second mailing and the telephone prompts, however, added          only marginally to the initial response. The majority of the returns received were in the          form of printouts. When reviewed for processing, many of these proved to          be incomplete or unclear in their presentation of key data items. The          identification of third-party payers and the amounts paid by third          parties were the data items most frequently missing. Variations in the          way the printouts were formatted and the manner in which data items were          labeled frequently resulted in ambiguity about the meaning of specific          items on the printouts, requiring some followup contact with the          pharmacy for clarification. To improve response at the levels of both the          pharmacy and the individual data items, the initial data collection          protocol was supplemented with a two-pronged telephone data collection          effort. One group of telephone interviewers concentrated on data          retrieval calls to pharmacies that had responded. Retrieval telephone          calls to collect missing data items or to clarify data on the printouts          were needed for nearly 70 percent of the responding pharmacies. A second          group of telephone interviewers concentrated on primary data collection          from the nonresponding pharmacies, adopting an approach similar to that          used for the MEPS Medical Provider Component (MPC) (Cohen, Monheit,          Beauregard, et al., 1996). These interviewers contacted pharmacies by          telephone, explained the data collection request, and faxed copies of          the permission forms and other relevant materials to the pharmacies.          Within several days of the faxing, they placed additional calls to          collect the requested data over the phone or to prompt their pharmacy          contact to send in the printed patient printouts. Most responding          pharmacies chose to mail or fax the printouts to the study. The bottom-up approach adopted for dealing with          the large pharmacy chains yielded mixed results. Many of the individual          pharmacies associated with chains responded directly to the initial          mailed request for data. However, as the telephone followup work          progressed, pharmacies for a number of chains referred interviewers to          regional or corporate offices. Corporate contacts reacted to the data          requests in several ways: some referred the interviewers back to the          individual pharmacies, with or without corporate endorsement of the          study; some chose to consolidate the projects requests and provide          data from a centralized location; and several of those that undertook an          effort to provide the information were unable to provide it on a timely          basis or abandoned the effort as too burdensome. The permission form response rate (that is, the          rate at which household respondents who were asked to sign permission          forms actually signed them) is shown below. Eligible person-pharmacy          pairs.......................20,023 Signed permission          forms.................................14,531 Permission form signing          rate...............................72.6 Table 1 shows response rates for the pharmacy data          collection. Response rates are shown at both the pharmacy level (72.2          percent) and the household patient-pharmacy pair level (67.1 percent).   Return to Top Data Editing, Imputation,  and Matching  The general approach to preparing the household          prescription data for public release was to impute information collected          from pharmacy providers to the household drug mentions. For SFs,          information on payment sources was retained if these data were reported          in the charge and payment section of the household questionnaire. A          matching program was developed to link drugs and drug information from          the PC to HC drug mentions. To improve the quality of these matches, all          drugs on the household files were assigned numeric codes from a          proprietary database on the basis of the medication names provided by          the household. These codes were also assigned to the prescriptions in          the PC by using the NDC, when available, and medication names reported          by the pharmacy providers. Considerable editing was done prior to the          matching to identify free samples among household drug mentions, to          correct data inconsistencies in both data sets, and to fill in missing          data and correct outliers on the pharmacy file. After the matching,          household drug mentions in Round 3 of MEPS, which spanned portions of          both 1996 and 1997, had to be allocated to each year to produce the          final annual prescription use and expenditure data for survey year 1996. Return to Top Drug Coding and Flat Files The initial task for the drug editing was to          assign a common set of drug codes to the household drug mentions and to          the prescription drugs reported by the pharmacy providers. Westat (the          MEPS data collection contractor responsible for collecting the pharmacy          data from the participating pharmacies and producing the initial HC and          PC files containing each separate drug purchase) contracted with Aspen          Systems Corporation to provide coding support services as a          subcontractor for the MEPS project. First DataBanks proprietary 1998          Master Drug Data Base (MDDB), which contains the Generic Product          Identifier (GPI) code, was selected for this task. The GPI is a 14-digit          code that contains 7 pairs of digits.   The first pair of digits          represents the drug group. Successive paired digits represent the drug          class, drug subclass, drug name, drug name extension, dosage form, and strength. Coders filled in as          many digits of the GPI as possible based on the medication name (and any          supplementary information appended to the name) provided by the          household, and the NDC, medication name, and other information provided          by the pharmacy provider. Typically, 8 to 10 digits were coded for          household-reported drugs, and all 14 digits were filled in for          pharmacy-reported drugs. Return to Top 
              	Table 1
              	          Pharmacy data collection response rate in the 1996 Medical Expenditure Panel Survey    
                  |  | Pharmacies | Person-pharmacy pairs |  
                  | Sample type | Number | Percent | Number | Percent |  
                  | Initial Sample | 6,109 | 100.0 | 14,531 | 100.0 |  
                  | Out of Scopea | 788 | 12.9 | 2,385 | 16.4 |  
                  | Net Sample | 5,321 | 87.1 | 12,146 | 83.6 |  
                  | Complete | 3,840 | 72.2 | 8,149 | 67.1 |  
                  | Refusal | 325 | 6.1 | 1,114 | 9.2 |  
                  | Other nonresponse | 1,156 | 21.7 | 2,883 | 23.7 |   a The category "out-of-scope          pharmacies" included establishments reported by a household          respondent that were not pharmacies (e.g., when the medicine was given          as a free sample in a physicians office), pharmacies located outside          the United States, originally reported pharmacies that merged with          another reported pharmacy during the data collection period, and          pharmacies whose associated sampled persons were out of scope. It also          included pharmacies that did not fill prescriptions for the sampled          persons in 1996 but may have done so in later years. A person-pharmacy          pair was treated as out of scope if the pharmacy to which the person was          linked was out of scope.  Note: The sample for the Pharmacy Component (PC) included all persons reported          to have had prescriptions filled or refilled during the first three          rounds of the Household Component (HC). For pharmacies reported in the          HC in Round 3, which overlapped the end of 1996 and the start of 1997,          the sample processing did not have respondents differentiate between          prescriptions obtained in 1996 and those obtained in 1997. This was not          true for what the PC pharmacies were asked and reported. PC pharmacies          were asked for 1996 data only. If, during data collection for 1996          prescriptions, a pharmacy acknowledged the person as a customer but          reported having filled no prescriptions for the person in 1996, the          person was treated as out of scope for 1996 pharmacy data collection          (but in scope for the 1997 data collection).                    
            Source: Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and          Quality: Medical Expenditure Panel Survey, 1996, public use file          HC-010A.          
           The second task for the prescription editing work          was to determine the MEPS variables to add to the household and pharmacy          event-level files for later use. Separate household event files were          constructed for drugs reported by households classified as SFs and for          drugs reported by households classified as NSFs. The additional data on          prescription charges and payments collected for the SFs, and the          additional processing this would entail, made this necessary. To          maintain consistency between the PC and HC databases, household-reported          drug mentions needed to be  unfolded into individual records; that          is, each prescription constituted an individual record, whether it was a          refill or an initial purchase. An individual record on the Pharmacy          Component file represented a single prescription purchase regardless of          whether the purchase represented an initial prescription or a refill.          For matching purposes, it was therefore necessary to create separate          records for each prescription, whether initial purchase or refill, on          the household event files. Variables added to the household SF and NSF flat          files, as well as to the pharmacy flat file, were critical to the          matching and editing/imputation processes. (Flat files are files in          which each record represents one prescribed medicine event, whether it          be an original prescription, a refill, or a free sample.) These          variables were: 
            Prescription event and person identifiers.Beginning and ending reference period dates for              each round.An indicator of private health insurance              coverage for prescription drugs by round.Potential source-of-payment indicators by              round.Whether a person was in a health maintenance              organization (HMO) by type of HMO (Medicare HMO, Medicaid or other              public HMO, or private HMO) by round.Conditions associated with prescription drugs              by round.Geographic division and region, in addition to              metropolitan statistical area (MSA) status.Various health status and demographic              characteristics. Additional variables added to the pharmacy flat          files included round-specific pharmacy identifiers and names and types          of pharmacy providers.   Return to Top  Preliminary HC Event Edits  The three flat files contained 15,804 SF drug          events for 1,562 persons, 188,422 NSF drug events for 14,629 persons,          and 84,029 PC drug events for 6,874 individuals. The individuals in the          SF and NSF groups were not mutually exclusive because 941 persons had          events in both files; however, additional analysis showed that no single          person was classified as both an SF and NSF in the same round. Excluded          from the flat files were 899 SF drugs, 6,691 NSF drugs, and 32 PC drugs          for persons in the preliminary MEPS Round 1 and Round 2 samples who were          not in the full-year population. These persons did not have          positive-valued full-year weights, nor were they related to anyone with          such weights. Remaining in the full-year population, however, were some          non-key persons who had zero person weights but were members of families          in which at least one individual on the full-year file had a          positive-valued person weight. For SFs, a preliminary set of edits based on          similar edits applied to other nonprescription MEPS expenditure events          was run on the household-reported data for each drug event. These edits          mostly relied on household variables created to classify actual payment          source variables or potential payment source variables. Actual payment          source variables were coded as "known payer, known amount          paid," "known payer, unknown amount paid," "not          known to be a payer," or " source not available."          Potential payment source variables were coded as "covered or source          available in round" or "not  covered or source available          to all in round." "Source available to all in round" was          the way the potential payment source variable for self-payments was          always coded. In addition, round-specific household variables indicating          whether the person was enrolled in a private health insurance plan          covering prescription drugs and whether the person was enrolled in a          Medicare HMO, a Medicaid or other public HMO, or a private HMO were used          in combination with other variables from the HC charge and payment          section to edit the data and/or correct for inconsistencies. The          purposes of these edits are summarized below. The number of events          affected by the edit is shown in parentheses. 
            Make it impossible for elderly persons enrolled              in a Medicare HMO plan to claim any source other than Medicare as a              source of payment for prescriptions (95 events). Equate the total charge to the sum of              payments if the two differed by $2 or less (126 events).Eliminate the inconsistency created from              persons mistakenly reporting private insurance when they actually              had Medicare HMO or Medicaid HMO insurance coverage (6 events).Correct inconsistencies between Medicare and              Medicaid reported as sources of payment and coverage (0 events).Correct inconsistencies between reported              insurance coverage during the year and potential coverage from              private insurance, Medicaid, Medicare, and CHAMPUS              (Armed-Forces-related coverage) (68 events).Assign a missing payment amount to self-pay              when no information was available to link the missing payment to a              third-party payer (2 events).Eliminate Medicaid as a source of payment when              sources other than out-of-pocket are present and when there is an              out-of-pocket payment greater than $5 (118 events). In a second set of preliminary edits on the          household drug event data for SFs, five edit rules were imposed in the          order shown below. Only one edit rule was allowed per event. For          example, if an event was edited because of the first rule listed, that          event would not be eligible for any of the editing rules that followed          the first rule. 
            Medicaid cases were processed so they would be              correctly classified for later imputation (131 events).The problem of having persons confuse              "other" source of insurance with private insurance              coverage was resolved (0 events).If total charge was reported to be $5 or              more, no payments were reported, and self-pay was the only missing              payment source, then self-pay was set equal to the total charge for              the drug product (24 events).If the payment sum exceeded $30 and no              payment sum information was reported as missing, then the editing              for the event was designated as completed (2,639 cases).If the payment sum exceeded $30 and was              within $5 of the total charge, and one payment source was missing,              then the missing payment amount was set equal to zero (43 events). During each round, households were asked in the          prescription drug section of the HC questionnaire whether they received          any free samples of prescribed medicines from any medical or dental          provider. If they responded in the affirmative, respondents were then          asked to name the medicines they received as free samples in a given          round. However, no information was reported on the number of drug events          for a given medication in a given round that were free samples. Initially, 693 prescription drug events for SFs          were deemed to be free samples. For a medicine to qualify as a free          sample for an SF, the following two conditions had to be met: (1) all          payment sources were reported as zero and (2) the household reported          receiving free samples of the medication. After 41 free sample Round 3          prescriptions of SFs were allocated to 1997, the final number of 1996          free samples for SFs in the MEPS HC was 652. (See the "Allocation          to 1996 and 1997" section, below.) For NSFs, 4,252 drug events initially were          designated as free samples. Only one drug event per round per drug          product was allowed as a free sample if the household reported receiving          free samples of the drug product during the round. If the person in the          NSF household was in the Pharmacy Component and the designated          "free sample" was later exactly matched to a prescription          purchase on the PC file, then the free-sample designation was          overridden. Of drugs originally designated free samples for NSF          households, 462 were later matched to prescription purchases on the PC          file. After 603 Round 3 prescriptions in MEPS were          allocated to 1997, the final number of free samples for NSFs in 1996 was          3,187.   Return to Top  Preliminary PC Event Edits  Some preliminary edits were imposed on the PC          data. They were patterned after similar edits applied to nonprescription          data collected in the MEPS Medical Provider Component. If, based on          information from the HC, a sampled person did not potentially have          coverage from a public or private insurance source, then any missing          code for the corresponding payment amount from the PC for a specific          drug event was coded as a zero payment (4,912 events). After this, the          sum of payments for a drug event on the PC was set to missing if any          payment sources were coded as missing (11,486 events). Additional edit rules to the PC drug events,          patterned after similar edit rules applied to the nonprescription MPC          events, were designed to do the following:  Rule P1: Correct information from pharmacies that mistakenly reported a private          insurance payment source instead of a Medicare HMO (406 events) or          Medicaid HMO (211 events) payment.                    
            Rule P2: Set          the total charge equal to the sum of payments if the two measures          differed by no more than $2 and none of the payments or the total charge          was missing (791 events).                    
            Rule P3: Allocate the excess of total charge over a partially reported payment          sum to a specific payment source either based on the pharmacys          identification of a single third-party source or based on potential          third-party coverage of the person (95 events).                    
            Rule P4: Eliminate an out-of-pocket payment when it appears that the pharmacy          provider shows an unlikely amount for a patient copayment that is equal          to the reported amount for Medicaid (18 events) or Workers          Compensation (1 event).                    
             Return to Top  Matching Software  From the outset of the MEPS prescription drug          editing work, it was clear that the hot-deck approach to imputing          missing data was not going to be appropriate for this task. Donor          hot-deck cells defined on the basis of a specific drug code or          medication name were too small to stratify by other variables deemed to          be correlated with the purchase of a specific drug product. Also, because the GPI codes encompassed numerous          specific drug products with different NDC values, it was clear that          software would have to be developed that could "read"          medication names from both donor and recipient files to improve the          quality of the matches. To meet these needs, the data processing          contractor, Social and Scientific Systems, Inc. (SSS), developed          software that imputed PC drug data to the household drug mentions by          matching drug events from each file based on variables with both numeric          characters (e.g., GPI codes, potential payment sources, age, sex, health          status, and geographic location) and alpha characters such as the          medication names supplied by the household and the pharmacy providers.          The matching software that SSS developed had the following          features:  
            An overall score ranging from 1 to +1 was              assigned to each donor drug that represented a potential match to a              recipient drug, with +1 representing the highest score attainable              when each match variable received the highest score possible.              Separate weights were assigned to the match variables to reflect              their importance relative to other match variables in determining              the final overall score. Values between 1 and +1 for final scores              were constructed as the weighted score for the match divided by the              weighted score when all match variables receive the highest possible              score. (An example is given in the next section.) Certain match              variables could be required to match exactly or a potential match              between drugs was not deemed possible.All numeric match variables had to match              exactly or no positive contribution was made to the final score for              the specific variable. A value of +1 was assigned in the event of              any exact match. A value of 1 was assigned if there was no exact              match.For words (alpha characters), the best match              was found according to the following hierarchy: The words matched exactly.The words sounded the same using a Soundex function. (The Soundex system          indexes names by how they sound rather than how they are spelled).
 A pair of characters was swapped in the third to last characters.
 Only one character was different in the third to last characters.
 The shorter word exactly matched the first          characters in the other word. The words started with the same characters.  None of the above. To resolve ties, except when the words started          with the same characters, the longer word was used. When the words          started with the same characters,  the word that started with more of the same          characters was used, and then the longer word was used if there were still ties. 
            For words (alpha characters), once the best              match was found, it was assigned a score measuring how closely the              words matched, and it was also assigned a weight indicating how              strongly a good or poor match should be considered. Except for an              exact match or a non-exact match where the words started with the              same characters, higher scores were assigned to matches between              longer words. For a non-exact match where the words started with the              same characters, the larger the portion of the words that matched,              the higher the score that was assigned. An exact match was given the highest score          regardless of the size of the word. 
             When there were ties among the final              scores, a random number between zero and one was generated to break              the ties, and the highest number assigned determined the final              match. After scrutinizing numerous examples of these ties, it was              determined that in general the ties reflected the lack of enough              information in the database to identify a uniquely best match. Under              these circumstances, giving each of the donors tied for first place              an equal chance for the final match seemed preferable to any further              experimentation with weights, match variables, or scores for alpha              variables to find the best match.The software allowed donor records to be              matched to recipient records either with or without replacement of              the donor records in the donor pool for subsequent matches.   Return to Top  Example of Matching  Suppose a household member reported a purchase of          "AMOX" in a given round of MEPS, and an attempt is made to          match a PC record of "AMOXICILLIN" to it. A total weight of          100 is assigned to the pharmacy name match. The group weight of 100 is          multiplied by 0.8 if the word is 4 characters long and by 1.0 if the          word is 6 or more characters long. In this example, comparing the HC          name to the PC name counts 80 toward the final score. Comparing the PC          name to the HC name has the potential to contribute 100 to the final          score, but because there is no match in this case, it contributes 100          to the final score. In this example, if the medication name is the only          match variable, then the final score equals 80100, or 20, divided          by 180, or .111.  In the same example, if an exact match is required          on the GPI code, then this case probably cannot even be in the running          for the best match. If an NDC were on the PC record for the "AMOXICILLIN,"          then a full 14- digit GPI code would have been assigned. With only          "AMOX" available on the HC record, at best only 6 of the 14          digits of the GPI could have been coded. In this example, weighted match variables (match          variables not requiring an exact match) for the 2-, 4-, and 8-digit GPI          code (with weights of 20, 40, and 80, respectively) could be added to          the match variable for the medication name. The total potential score          for the match becomes 320 rather than 180 with the addition of the          weighted match GPI variables. Assuming that only the first 4 digits of          the GPI matched between the HC and PC drug purchase, then the final          score for the attempted match becomes 20+20+4080, or 40,          divided by 320, which equals .125.   Return to Top  NDC Imputations  In order to identify potential outlier drug prices          on the PC database, it was necessary to add the average wholesale unit          price (AWUP) from the MDDB database to the PC file. This was achieved by          performing a crosswalk from the PC file to the MDDB file through the NDC          to retrieve the AWUP on the MDDB file. This, however, presented a          problem for the 4,604 PC drug events that had missing or unclassified          NDC values. In addition, another 8,266 PC drug events had reported NDC          values that did not match any NDC on the MDDB database. For these          reasons, it became necessary to impute NDC values to these 12,870          records. All but 498 of the 12,870 PC drug events that          could not be linked by NDC to the MDDB data had previously been assigned          a GPI code. For the 12,372 cases with a GPI, the matching software was          utilized to find the best match to a drug product on the MDDB based on          the GPI and the medication name on the PC file. Because a single GPI may          cover multiple drug products with differing NDC values, medication names          from the PC file were also used as match variables against both the          generic and trade/brand names of drugs on the MDDB file. Quantity units,          strength, and strength units were also available from the MDDB file and          were used as match variables. For 10,462 of the 12,372 PC drugs with GPI codes,          NDC values from reasonable matches to the MDDB file were imputed to the          PC file by requiring an exact match  to the full GPI and by also          using the medication name as a match variable. Another 1,894 drug events          were imputed by an exact match to the first 8 characters of the GPI and          by again using the medication name as a match variable. The 16 PC drug          events with a GPI that did not match in either of the imputation runs          above were sent through a matching routine without requiring an exact          match on any portion of the GPI. For 9 of these cases, the best match          selected by the software was used. Three of the remaining 7 cases were          hand-matched to one of the top 10 choices from the software output. Four          cases remained. For 2 records the NDC was hand-coded to a specific NDC          and for 2 others a matching program was run to find the NDC matching          "orthonovum." For the 498 PC drugs lacking a GPI code, the          71,159 PC drugs with a valid reported NDC were used as the donor base          for the matching software. Match variables included the persons age,          sex, geographic division, MSA status, health conditions, potential          payment sources, and SF/NSF status. Most of the 498 PC drug events          lacking a GPI code were also missing the drug name, as well as specific          information regarding the quantity and strength of the drug. This          explains why these drugs were never initially assigned a GPI code. Match          donors from the PC file were restricted to those with non-missing drug          product names. The medication names, along with the GPI and quantity and          strength information from the donor record, were merged into the          recipient drug record whenever this information, in addition to the NDC,          was missing from the recipient record. The quality of the matches was not as high for the          2,408 PC drugs for which there was not an exact GPI code match between          donor and recipient. Therefore, these PC drugs were later removed from          the donor pool for all matches between HC and PC drug events that were          run with replacement. The initial matches, as discussed below, were run          without replacement to identify exact matches between HC and PC drug          events for the same person in the same round of the survey. The only          drug events in the donor pool for these matches were whatever drug          purchases were reported by the persons pharmacy provider(s) in the          PC.   Return to Top  Other PC Imputation  In order to screen for drug price outliers, a          retail unit price (RUP) was constructed from the Pharmacy Component data          and compared against the AWUP taken  from the MDDB file. The RUP          was constructed as the retail price for the drug product, defined as the          sum of payments for the prescription divided by the dosage amount or          quantity dispensed as reported by the pharmacy provider. For 75 of the          84,029 PC drug events, the amounts dispensed were missing. The matching          software was used to impute these missing quantities. Match variables          included the NDC and GPI for the drug product and the persons age,          sex, health conditions, and health status. Exact matches for the           first eight characters of the GPI were required and heavier weight was          placed on the NDC, followed by the GPI. For 211 drug products, reported dosage amounts          contained more than one value. Values were typically separated by a          slash or dash on the computer printouts supplied by the pharmacy          providers. Pharmacy consultants to Westat, Mediquest Associates,          provided technical assistance in establishing editing rules to determine          the appropriate value to use for the dosage amount in these cases. For 206 drug products, the round in which the          prescription was purchased was missing from the PC file. This variable          was initially prepared for the PC flat file, but because of missing          month (168 events), day (173 events), and/or year (14 events)          information for certain prescriptions on the file, the round variable          was missing. The matching software was used to impute the round for 110          events, using the person identifier as an exact match and the NDC and          GPI as weighted match variables. The remaining 96 events were imputed a          value for the round by a second application of the matching software.          During this second application, the variables for the year at the          beginning and the end of the round were exact matches and the year at          the beginning of the first round was a weighted match variable. The AWUP variable was then merged onto the PC file          from the MDDB database by NDC value. Up to six AWUP values, measured at          different times, were provided on the MDDB file. Prices dated the          closest to the middle of 1996 were selected, but in some cases only          prices for years prior to or after 1996 were available. Distributions of          the ratio of RUP to AWUP (called PRATIO) for cases in which the merged          AWUP was dated before 1996, in 1996, and after 1996 were analyzed to          determine whether adjustments were needed for the outlier analysis.          Depending on the measure used for the price variable on the PC file          (described below), AWUP prices before 1996 were inflated by either 10 or          40 percent to produce a PRATIO distribution comparable to one using only          1996 AWUP values.   Return to Top  Outlier Editing  After the preliminary editing described above was  performed on the PC file, three different measures of the retail price of the  drug product were constructed:2 PRICE1 = the sum of payments when no payments  were coded as missing (68,664 events) PRICE2 = the sum of payments when at least  one payment is reported greater than zero and at least one payment is reported  as missing (8,030 events) PRICE3 = the reported total charge for the drug  product when reported to be greater than zero and all payments are reported to  be either missing or zero (2,141 events) The remaining 5,194 drug products on  the PC file (referred to as PRICE4 cases) lacked any positive-valued payments or  total charge data. 
  2 Recall that from rule P2 (Preliminary PC Event Edits  section), the total charge was set equal to the sum of payments when the  difference between the two was no greater than $2 and none of the payments or  the total charge was missing. Based on PRICEn values (n = 1,2,3), the 78,835 drug events  with a positive-valued price were sorted into three groups for outlier  analysis:  PRGRP1n = 1 if PRICEn = self-payment and PRICEn <= $30  (32,528 events) = 0, otherwise  PRGRP2n = 1 if PRICEn = self-payment and PRICEn > $30  (7,788 events) = 0, otherwise  PRGRP3n = 1 if PRICEn does not equal self-payment (38,519  events) = 0, otherwise The 78,835 drug products were next allocated to three  outlier groups based on PRATIOn, the ratio of retail unit price (RUPn) to AWUP  (using PRICEn, n = 1,2,3 and dosage amounts to construct RUPn), as follows:   OUT1n = 1 if PRATIOn < .8 (22,002 events) = 0, otherwise OUT2n = 1 if .8 < =PRATIOn < 20 for n = 1 and AWUP  before 1996 or if .8 <= PRATIOn < 10 otherwise (56,293 events) = 0, else OUT3n = 1 if PRATIOn >= 20 for n = 1 and AWUP before  1996 or if PRATIOn >= 10 otherwise (540 events) = 0, else The thresholds for determining unit price outliers were  established after consulting with Mediquest Associates, Inc., Westats  pharmacy consultant experts for the study. An additional 14 edit rules for the prices and payment  sources on the PC file were implemented based on the PRICE, PRGRP, and OUT  classifiers. These edit rules, described below, are labeled Rule P5 to Rule P18. Outlier cases were edited by setting the outlier RUP equal  to the AWUP. Tabulations of the PRATIO distribution for non-outlier  prescriptions verified that the AWUP was the modal value for the distribution.  Rule P5: PRICE1/PRGRP11, PRGRP21, and PRGRP31/OUT21 (53,351 events).  
           This edit rule stated that when no payment sources were  missing and when the drug price was equal to a positive-valued sum of payments  and not an outlier, no edit was required. Payment shares were constructed for  these cases for use in implementing editing rule P7.  Rule P6: PRICE2/PRGRPm2/OUT22 (m = 1,2,3) (1,261 events).  
           This edit rule stated that if at least one payment source  was missing but the others summed to a positive amount, then no edit was  required if the sum was not an outlier price, unless the sum was less than the  total charge. In the latter case, the drug price was set equal to the total  charge. The new price was checked to make sure it was not still an outlier  price. If it was an outlier price, then it was reclassified and edited by  another appropriate rule (P15 or P17). If it was not an outlier price, then a  single missing payment source was set equal to the difference between the total  charge and payment sum. If more than one source was missing, a hierarchy was  established for deciding which missing source would be allocated the difference.  In the hierarchy, Medicare was allocated as payer if the person was 65 or older  and was in a Medicare HMO; otherwise, Medicaid was allocated as payer if the  person had Medicaid coverage; otherwise, private insurance paid the difference  if the person had private coverage; and so on. After editing, payment shares  were constructed for each drug event for use in implementing editing rule P7.  Rule P7: PRICE3/PRGRP33/OUT23 (1,681 events).  
           This edit rule was applied to drug events for which the  drug price equaled a positive-valued total charge variable. The payment sum was  zero or missing because no payment sources were positive valued. When the drug  price (total charge) was not an outlier, payment source amounts were assigned by  payment shares merged onto the event record by matching to another non-outlier  drug event record (from P5 and P6) containing clean payment amounts. The exact  match variables were the potential payment sources, a variable for whether the  person had private prescription drug coverage, and the persons sex. The  weighted match variables were the drug products GPI, NDC, and price, and the  persons age, region, and MSA status. Before matching, the potential payment  source flags were set to indicate coverage from a given source if the payment  amount for the drug product on the PC record was greater than zero.  Rule P8: PRICE4  (cases lacking any positive-valued payments or total charge data) (5,194  events).  
           In cases in which the total charge was missing or zero and  there were no positive-valued payment amounts, the drug price and payment source  amounts were imputed to the PC drug event record by a match to a donor drug  event record. The donor records consisted of PC drug events in which at least  one payment amount was positive valued and the drug price was not an outlier (P5  and P6 events). Initially 1,447 of these cases were matched by using exact match  variables for the NDC and GPI of the pharmaceutical, the potential payment  source flags, and an indicator of private prescription coverage for the person.  Weighted match variables included the drug name, the pharmacy name, and the  persons age, sex, geographic region and division, and MSA status. Because of  the high quality of these matches, the donor records dosage amount was also  imputed to the P8 recipient record to avoid creating new price outliers  unnecessarily. No replacement for the recipient dosage amount was imputed in the  remaining matches because the quality of the matches was not as good. In a  second match, the first six GPI characters replaced the full GPI and full NDC as  exact match variables from the first match, and sex was used as an exact match  variable. This produced 2,397 more matches. An additional 602 P8 records were  matched in a third run, in which the first two GPI characters replaced the first  six GPI characters from the second run as an exact match variable. All but 25 of  the 748 remaining unmatched P8 cases were matched in a fourth run, in which the  GPI was omitted altogether as an exact match variable. The remaining 25 cases  were hand edited by assigning them a retail drug price equal to the product of  the AWUP and the dosage amount from their own record. Based on the name of the  pharmacy provider, which identified it as a Veterans Affairs (VA) or military  pharmacy provider, and the potential coverage variables, the entire imputed  purchase price of each of the 25 drug products was assigned to either VA or  CHAMPUS coverage.  After all prices were imputed to P8 cases, 1,838 new  outliers were created by combining the prescription price from the donor record  and the dosage amount from the recipient record of the 3,747 drug events that  failed to match in the initial run of the matching software. These 1,838 outlier  events were further edited by one of the five remaining "PRICE1" edit  rules (i.e., Rules P9-P13). Further analysis of the names of the pharmacy providers  for P7 and P8 drug events showed that a substantial majority of them appeared to  be VA, CHAMPUS, or "other Federal/Indian Health Service" providers.  These pharmacy providers generally do not know the charges and payments for  specific prescriptions. At this point, any P7 or P8 drug event in which the  words VETERAN, VETERANS, VETRANS, VA, or VAMC appear in the name of the pharmacy  provider and the person reported VA as a potential coverage source was assigned  VA as the sole payer of the purchase price of the drug product. Any P7 or P8  drug with ARMY, AFB, NAVY, NAVAL, NAVCARE, MARINE, USAF, or AIR FORCE in the  pharmacy provider name and CHAMPUS as a potential coverage source was assigned  CHAMPUS as the sole payer of the purchase price of the prescription product. If  the person indicated "other Federal," and not CHAMPUS, as a potential  payment source, then the full amount paid was assigned to other Federal rather  than CHAMPUS. Finally, if INDIAN or TRIBAL (other than INDIAN RIVER or  INDIAN TRAILS) appeared in the pharmacy name of a P7 or P8 prescription and  other Federal was reported as a potential payment source, then the full purchase  price of the drug product was assigned to other Federal.  Rule P9: PRICE1/PRGRP11/OUT11 (8,121 events).  
           This edit identified cases in which the RUP was under 80  percent of the AWUP, self-payment was the sole positive payment amount reported,  no other source had a missing code, a corresponding potential source was  indicated, and the self-payment was $30 or less. In the edit the RUP was  increased to the AWUP. The size of the self-payment in these cases suggested a  copayment situation. Therefore, the difference between the new and old retail  price for the drug was allocated hierarchically to any potential third-party  sources indicated for the person. If none was indicated, then the full retail  price increase was allocated to self-payment.  Rule P10: PRICE1/PRGRP21/OUT11 (657 events).  
           This drug edit identified outlier drug prices in which the  RUP of the drug was under 80 percent of the AWUP. The RUP of the drug was edited  by increasing it to the AWUP. The resulting increase in the retail price of the  drug was allocated entirely to self-payment because it was the only payment  source indicated by the person purchasing the drug and because the reported  amount was over $30 and not considered a potential copayment case.  Rule P11: PRICE1/PRGRP11 and PRGRP21/OUT31 (231 events).  
           In these cases, the reported RUP of the drug equaled or  exceeded 10 times the AWUP (or 20 times the AWUP if the AWUP was measured before  1996). In this edit, the reported RUP was reduced to the AWUP. The subsequent  reduction in the retail price of the drug was taken entirely out of the  self-payment amount because it was the sole payment source with a positive  amount reported for the individual.  Rule P12: PRICE1/PRGRP31/OUT11 (7,575 events).  
           For cases in which the RUP was less than 80 percent of the  AWUP, the reported RUP was increased to the AWUP. A hierarchy was established  for allocating the increase in the retail price of the drug to a single  positive-valued payment source because there might have been more than one  payment source with a positive amount reported. In the hierarchy, any  third-party payer had a higher priority than a self-payer.  Rule P13: PRICE1/PRGRP31/OUT31: (567 events).  
           For cases in which the RUP was greater than or equal to 10  times the AWUP (or 20 times the AWUP if the AWUP was measured before 1996), the  RUP was decreased to the AWUP. A hierarchy was established for allocating the  decrease in the retail price of the drug to a single payment source because  multiple sources might have been reported with positive amounts. If the entire  decline in the retail price was not used up in these cases by one payment  source, the remainder was taken from the next source in the hierarchy. This  allocation process continued until the entire price reduction was fully  allocated.  Rule P14: PRICE2/PRGRP12 & PRGRP22/OUT12 (6,726 events).  
           In this case, at least one potential third-party payment  source was missing and the self-payment amount, the only positive-valued source  of payment reported, initially was set equal to the retail drug price. If the implied RUP was less than 80 percent of the AWUP,  then the RUP was inflated to the AWUP. The difference between the new and old  retail drug price was allocated entirely to the missing third-party payer if  only one was missing. If more than one third-party payer was missing, then a  hierarchy was established to allocate the entire difference to one of the  missing payers.  Rule P15: PRICE2/PRGRP12 & PRGRP22/OUT32 (15 events).  
           In this case, the RUP equaled or exceeded 10 times the  AWUP. The self-payment equaled the retail price of the drug, although at least  one third-party payment was reported as missing. The RUP was reduced to the AWUP,  and the reduction in the retail price of the drug was taken entirely out of the  out-of-pocket payment reported by the pharmacy provider.  Rule P16: PRICE2/PRGRP32/OUT12 (25 events).  
           In this case, self-payment was not the sole  positive-valued payment amount, but there was at least one missing payment  amount and the RUP was less than 80 percent of the AWUP. The RUP was inflated to  the AWUP, and the retail drug price increase was allocated to the missing  payment source if only one source was missing. A hierarchy that included  self-payment was used to allocate the drug price increase to missing payment  sources when more than one source was missing.  Rule P17: PRICE2/PRGRP32/OUT32 (3 events).  
           In this edit, the RUP equaled or exceeded 10 times the  AWUP. At least one potential payment source was missing but at least one was  positive valued. Self-payment was not the only positive-valued source reported.  The RUP was deflated to the AWUP, and the reduction in the retail drug price was  removed from reported positive-valued payment sources in the same way as in  editing rule P13.  Rule P18: PRICE3/PRGRP33/OUT13 and OUT33 (460 events).  
           In this outlier edit, the retail price was the reported  total charge when it exceeded zero and no reported payment amount was positive  valued. The RUP either was less than 80 percent of the AWUP, or it equaled or  exceeded 10 times the AWUP. The RUP was set equal to the AWUP, and the new price  was allocated to potential payment sources by payment shares merged into the  event record by matching to a non-outlier drug event record containing clean  payment data. The sum of the records affected by PC edit rules P5  through P18 is 85,867, 1,838 more than the 84,029 PC drug events. The 1,838  difference between these totals represents the Rule P8 cases in which an imputed  prescription price, combined with the dosage amount on the original record,  produced an outlier requiring additional editing by one of the PRICE1 rules, P9  through P13. After these edit rules were implemented, analysis of the  results revealed that for 530 OUT1 cases, the edited retail price for the drug  product was inflated to be inordinately high (in excess of $200) compared to its  original retail price, and for 697 OUT3 cases, the edited retail price for the  drug product was deflated to be inordinately low (under $2) in comparison to its  original retail price. The majority of these cases occurred when NDC values were  imputed for PC drug products and created mismatches among retail drug prices,  dosage amounts, and the AWUP to create the outlier PRATIO values. Because most  of these cases were not going to be used for imputation to household events,  they were edited by using the original retail price reported by the pharmacy  provider in combination with an edited dosage amount for these 1,227 PC events.   Return to Top  Self-Filer Matching and  Imputation  After cleaning the PC database, the next step was to match  or impute PC data to the HC drug mentions of SFs by using the matching software  in a series of applications. The first matching run was set up to identify exact  matches between prescription events mentioned by the household respondent and  reported by the individuals pharmacy provider. For this task, 6,356 PC  potential donor events were tested for exact matches to 8,223 HC prescription  mentions (not including 361 free samples) for SF households that were in the  linked pharmacy followback survey. The exact match variables in the first run  were the persons identification number (PERSID), the GPI, and the round in  which the drug was purchased. The weighted match variable was the medication  name supplied by the household and by the pharmacy provider. In the first run,  512 HC prescription mentions were exactly matched to prescriptions reported for  the same person in the same round in the pharmacy database. Once a match was  made, the PC donor was effectively removed from the donor pool and not matched  with any other HC drug mentions by the individual (i.e., the matches were made  without replacement). In a second run, exact matches were identified for an  additional 4,495 HC prescription mentions for SFs by requiring exact matches  only for the PERSID and the round, and by using weighted match variables for the  medicine name and the first 2 consecutive characters, first 4 consecutive  characters, first 8 consecutive characters, and first 10 consecutive characters  of the GPI code. After being reviewed, only 3,446 of these matches met the final  criteria for an exact match (a match score greater than zero, an exact match on  the first 4 consecutive characters of the GPI code, or an exact match on the  medicine name). The quality of the 1,049 matches that did not meet these  criteria was deemed too low to be classified as an exact match. Another 2,028 HC drug mentions of SFs were  "refills" associated with one of the 3,958 exactly matched HC drug  mentions and were matched to the same PC drug donor event as the exactly matched  event. (Although the term "refill" is used in this context, the MEPS  HC did not collect sufficient information to determine which drug acquisitions  were original prescriptions and which were refills in a given round of the  survey.) Refill drug records for an individual on the HC file were linked  through a common, round-specific event identification number (EVNTID). In case  two or more HC prescription records with the same EVNTID were exactly matched to  two or more separate PC records, any other unmatched refills with the same  EVNTID were matched by random selection to one of the exactly matched PC events.  This left 2,237 unmatched HC prescription mentions by SFs who participated in  the MEPS PC, in addition to 6,888 prescription mentions (not including 332 free  samples) for SFs not in the PC that remained unmatched.3 The remaining 9,125 unmatched HC-reported prescriptions  were eventually imputed data from a PC prescription drug through a series of  matching runs that included all 81,621 PC drug records in the donor base that  either did not require any NDC imputation or had an NDC imputed with an exact  GPI match. In these matches, if a PC drug was selected for an imputation, it  went back into the donor pool and was made available for subsequent imputations  (i.e., the remainder of the SF imputations were done with replacement). The 9,125 unmatched HC drugs contained 4,066 unique EVNTID  values. Each EVNTID contained at least one unmatched non-free prescription or  prescription refill. Of these EVNTIDs, 447 were imputed PC records by using the  GPI as an exact match variable. Weighted match variables, in descending order of  the weights, included the medication name; potential payment sources and private  prescription coverage indicators for the person; name of the persons pharmacy  provider(s); and the persons age, sex, condition codes, geographic region and  division, MSA status, employment status, and self-reported health status. PC  records were imputed based on a match on the first 10 digits of the GPI code for  2,931 EVNTIDs, based on a match on the first 8 digits of the GPI for 19 EVNTIDs,  based on a match on the first 4 digits for 323 EVNTIDs, based on a match on the  first 2 digits for 110 EVNTIDs, and based on a match on no portion of the GPI  for 236 
  3 A total of 15,111 HC drug mentions of SFs were  imputed PC prescription data in this part of the editing. Initially, there were  15,804 HC drug mentions of SFs. The difference of 693 between these two totals  represents SF drug acquisitions identified as free samples. EVNTIDs. All HC drug mentions with an EVNTID in common  were imputed values based on the match to a single PC donor drug product.   Return to Top Self-Filer Payment Reconciliation  For SF households, charge and payment information after  matching or imputation was available from both the self-reported household data  and from the data merged onto the prescription drug record from the PC  prescription donor record. The financial data were reconciled as follows:  
            If none of the household-reported payment amounts       were missing and the HC payment sum equaled the PC payment sum, then the HC      payment amounts were used along with the HC payment sum (63 events). If none of the household-reported payment amounts      were missing and the HC payment sum was greater than zero but did not equal      the PC payment sum, then the PC payment amount was used and the payment      amounts were allocated according to the shares for each amount based on the      HC data (10,984 events). If the HC payment sum was missing because at      least one payment source was missing, then the PC payment sum/price was used      along with the PC payment amounts if all of the HC payment amounts were      missing. If at least one of the HC payment amounts was not missing and the      sum of the non-missing HC payment amounts exceeded the PC payment sum, then      the HC payment amounts were used after scaling by the ratio of the PC      payment sum to the "partial" HC payment sum. If at least one of      the HC payment amounts was not missing and the sum of the non-missing HC      payment amounts was less than the PC payment sum, then the difference was      allocated to the missing HC payment source. If more than one HC payment      source was missing, then the difference was assigned hierarchically in the      following descending order: Medicare HMO, Medicaid, private insurance, VA,      CHAMPUS, other Federal coverage, State or local coverage, Workers      Compensation, other insurance, or self-payment (3,525 events).If the HC payment sum was zero with no missing payments      indicated, then the PC payment sum and amounts were used (539 events). In      general, an attempt was made to retain as much information as possible      regarding source-of-payment shares from the household-reported data.      However, the retail drug price information, which had been edited for price      outliers on the PC database, was provided from the PC data. Using the PC      retail prices instead of the HC payment sums avoided doing additional      editing of potential HC outlier prices and kept detailed drug identification      and pricing information from the PC intact when it was imputed to the HC      drug mentions. In general, an attempt was made to retain as much  information as possible regarding source-of-payment shares from the  household-reported data. However, the retail drug price information, which had  been edited for price outliers on the PC database, was provided from the PC  data. Using the PC retail prices instead of the HC payment sums avoided doing  additional editing of potential HC outlier prices and kept detailed drug  identification and pricing information from the PC intact when it was imputed to  the HC drug mentions.   Return to Top  Non-Self-Filer Matching and Imputation  Data on matching and imputation for NSF information are  shown in Table 2. The procedure used to match HC prescription mentions for NSF  households to PC prescriptions mirrors the procedure described above for SFs. As  with SFs, the first set of matches was designed to find exact matches between  the HC and PC drug events. The recipient HC database for these matches contained  108,353 prescription mentions, while the donor PC database consisted of 72,615  drug product purchases for NSFs. Drug mentions that had been identified as free  samples also were included in the HC recipient group of drug mentions for NSF  exact matches because of the rather arbitrary way in which a specific drug  mention was identified as a free sample for the NSF population. (See Preliminary  HC Event Edits section.) Even when only one prescription was reported for a  medication in a given round and the household reported receiving a free sample  of the drug, it was not clear whether the free sample was reported as the single  drug acquisition. This was not clarified in the interview. In the first exact matching run, 5,950 of the HC drug  mentions for NSF households in the linked PC followback were matched exactly and  without replacement to PC drug mentions by using the PERSID, the complete GPI  code, and the round of the drug as exact match variables, and the medication  name as the weighted match variable. In the second run for exact matches, 50,566  additional HC drug mentions were matched without replacement to PC drug records;  only PERSID and the round were required to match exactly, and the first  2-character, 4-character, 8-character, and 10-character GPI codes were used as  weighted variables. As in the SF matching, not all second-run matches were  retained. Only 37,405 of these NSF matches in the second run were deemed to be  exact matches because  they either had a match score greater than zero,  matched exactly on the first four characters of the GPI, or matched exactly on  the medication name. Of the 2,279 HC drug mentions designated as free samples  for NSF households in the PC followback, 462 were selected as exact matches and  are included in the count of the 43,355 exact matches. Next, an additional 23,838 unmatched drug refill mentions  by NSF household respondents in the PC were matched to one of the 43,355 PC  drugs that had been exactly matched to a purchase of the same drug by the same  person in the same round. This produced 67,193 matches to the original 188,422  drug mentions by NSF household respondents. Of the remaining 121,229 unmatched  NSF drug mentions, 3,790 were set aside as unmatched free samples, leaving  117,439 HC drug mentions unmatched for all NSF households (39,343 for households  in the PC and 78,096 for households not in the PC), representing 47,705 unique  EVNTID values. These 47,705 EVNTIDs were eventually imputed values from  PC prescription drugs through the same general series of matching runs without  replacement as for SFs, described above. The donor pool for these matches  consisted of 81,621 PC prescriptions, the full 84,029  sample  minus the 2,408 drugs with an imputed NDC that had no exact match to the GPI  code. In the first NSF imputation without replacement, which  required an exact match with the full GPI, 5,624 of the 47,725 EVNTIDs were  matched. In the subsequent imputations, 32,066 of these EVNTIDs matched on the  first 10 digits of the GPI; 274 matched on the first 8 digits; 4,746 matched on  the first 4 digits; 1,854 matched on the first 2 digits; and 3,161 did not match  on any portion of the GPI. After the matches were linked to every unmatched  refill with the same EVNTID, all 117,439 previously unmatched HC drug mentions  of the NSF population were imputed a PC prescription record. Because no charge  and payment data were collected in the HC for the NSF population, there was no  need to reconcile charge and payment data from the two sources after the  matching and imputation.   Return to Top  Unmatched PC Data  In the PC donor database of 81,621 drugs (all 84,029 PC  drugs less the 2,408 excluded from the matches with replacement), over  one-third, or 29,871 drugs, were never imputed or matched exactly to an HC drug mention. Because this number is close to the 25,666  refills of household drug mentions that were exactly matched to PC  prescriptions, an exercise was undertaken to determine how many of the unimputed,  unmatched PC drug purchases could be matched to the imputed, matched PC drug  purchases by NDC, GPI, and medication name. Results of this exercise confirmed the hypothesis that the  vast majority of the unmatched PC drug purchases were duplicates, or refills, of  PC drug purchases that were matched to HC drug mentions. Using NDC and GPI as exact match variables, and the  medication name, prescription price, and potential payment sources (in  descending order) as weighted match variables, 25,908 of the 29,871 unmatched PC  drug purchases matched to one of the 51,750 PC donor drug purchases. Of the  remaining 3,963 unmatched PC drug purchases, 3,699 matched to a PC donor by  using only the GPI as an exact match variable and the same partial match  variables as before. All but 2 of the remaining 264 unmatched PC drug purchases  were ultimately matched to one of the PC donor purchases by successively  reducing from 8 to 2 the number of digits in the GPI that were required to match  exactly. The final two PC drug purchases were matched to a PC donor by not  requiring any exact match variables and using only partial match variables for  the drug name, prescription price, and potential payment sources. The average prescription price for PC drug purchases that  were not matched or imputed to any HC drug mentions was $32.87. This was close  to $5.00 less than the average price of PC drug purchases that were matched or  imputed to HC drug mentions one or more times ($36.53). Of the latter 51,750 PC  drug purchases, 2,794 were matched or imputed five times or more to HC drug  mentions. These drugs had an average prescription price of $31.51. The 48,956 PC  drugs that were matched or imputed to HC drug mentions from one to four times  had an average prescription price of $36.82. The PC drug purchases that were not  matched or imputed to HC drugs had slightly lower average out-of- pocket and  private insurance payment shares (38.3 and 39.9 percent, respectively) than  those of PC drug purchases that were matched or imputed at least once (40.6 and  41.7 percent, respectively). PC drug purchases that were not matched or imputed  to HC drug mentions also had slightly higher Medicaid and other payment shares  (14.8 and 7.0 percent, respectively) than those of PC donor drug purchases (12.0  and 5.7 percent, respectively). This suggests that if all of the PC prescription  drugs had been matched or imputed to HC drug mentions, the average HC  prescription price and aggregate prescription expenditures, out-of-pocket  payments, and private insurance payments would have been slightly lower, and  aggregate Medicaid and other public prescription expenditures would have been  slightly higher. Return to Top 
           Table 2 
          Matching and imputation for non-self-filers in  the 1996 Medical Expenditure Panel Survey 
              | Number | Description |  
              | 188,422 | HC drug mentions by NSFs |  
              | 80,069 | HC drug mentions by NSFs without PC data |  
              | 108,353 | HC drug mentions by NSFs with PC data |  
              | 43,355 | Exact matches of HC drug mentions by NSFs to PC        data (includes 462 free samples that were exactly matched to PC drugs) |  
              | 23,838 | "Refills" (additional acquisitions) of        exact matches of HC drug mentions by NSFs |  
              | 41,160 | HC drug mentions by NSFs with PC data still unmatched |  
              | 121,229 | HC drug mentions by NSFs with  and without PC data still unmatched  (includes 3,790 free samples that remain unmatched) |  
              | 117,439 | HC drug mentions by NSFs that were imputed a PC drug        in matches "with replacement" (excludes 3,790 unmatched free        samples) |  Note: HC  is the Household Component of the Medical Expenditure Panel Survey (MEPS). NSF  is non-self-filer (someone whose pharmacy automatically sends the insurance  company claim form for prescriptions or handles third-party payments  electronically at the point of sale). PC is the Pharmacy Component of MEPS.  Source: Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality:  Medical Expenditure Panel Survey, 1996, public use file HC-010A.                      
              Return to Top Allocation  to 1996 to 1997  After all SF and NSF prescription mentions in the MEPS HC  were matched to PC prescriptions, Round 3 drug mentions that were not exactly  matched to PC drug products were allocated to either 1996 or 1997. As mentioned  earlier, the Round 3 survey spanned both years for respondents, and reported  prescription purchases in the HC were not dated within the round unless they  were matched exactly to a PC drug record. Each Round 3 drug mention that was not exactly matched was  allocated to 1996 or 1997 by using the beginning and ending dates of Round 3 for  each person and the percentage of Round 3 covering 1996 and covering 1997, in  combination with a random draw between 0 and 1. For the HC population, 12,923 of the 77,110 Round 3  prescriptions were exactly matched to PC drugs and classified as 1996 drug  purchases. Of the remaining 64,187 prescriptions, 52.0 percent (33,394  prescriptions) were classified as 1996 drug purchases using the random  allocation method, while the other 48.0 percent (30,793 prescriptions) were  classified as 1997 drug purchases. Return to Top Sensitivity  Testing  The edit rules imposed on the PC donor database described  above, on balance, were likely to increase the average retail price of  prescriptions because substantially more PC drugs were outliers at the low end  of the distribution (22,002 PRATIO values below .8) than at the high end (540  PRATIO values above 10 or 20). Of particular concern were the outlier cases at  the low end of the distribution that were classified as not missing any payment  sources (PRICE1 cases). Furthermore, there was some evidence to suggest that, in  certain situations, the outlier PRATIO value may have been caused by a  misreported dosage amount rather than a misreported price in the PC. To analyze  the sensitivity of national estimates of prescription expenditures to the  outlier edits,  alternative estimates were made by successively undoing  various outlier unit price edits that had been performed on the PC data. The national estimate of prescription expenditures in 1996  for the MEPS population before any changes were made to the edit rules described  above was $75.4 billion. The edits reversed were all edits to drug prices reported  without any missing payment sources (PRICE1 cases). A hierarchy was established for undoing the edits such  that the most likely candidates for a quantity edit rather than a price edit had  their price edits reversed first. Reversing the 7,575 lower end edits under rule P12, in  which no payments were missing and the original retail price/payment sum did not  equal the out-of-pocket payment, lowered the national prescription expenditure  estimate by $3.7 billion to $71.7 billion. Reversing the 657 lower end edits  under rule P10, in which no payments were missing and the original retail  price/payment sum equaled the self-payment but was greater than $30, lowered  national prescription expenditures by another half billion dollars to $71.2  billion. The final lower end edit that was reversed when no payment  sources were reported missing involved the 8,121 rule P9 cases in which the  retail price/payment sum equaled the self-payment amount and was less than or  equal to $30. These are more likely to be outlier retail price cases because the  low price and 100 percent self-payment suggest a copayment coupled with a unit  retail price less than 80 percent of the AWUP. Undoing this edit reduced the  national prescription expenditure estimate by another $4.6 billion to $66.6  billion. Finally, undoing the two higher end price edits in which  no payment sources were missing for the 798 events edited under rules P11 and  P13 increased the national prescription expenditure estimate by $.1 billion to  $66.7 billion. As suspected, the PC pricing edit rules on the linked  pharmacy followback data for cases in which no payment source amounts were  reported missing had an impact on the national prescription expenditure estimate  from the MEPS data. For the public use data (the 1996 Prescribed Medicines File,  HC-010A), the middle estimate of $71.2 billion was selected. For this  estimate,  pricing edit rules P9, P11, and P13 were left intact, but  pricing edits P10 and P12 were replaced by quantity/dosage amount edits. New  dosage amounts were imputed by dividing the original retail price of the   drug by the AWUP. Price changes for PC prescriptions that were matched to SFs  required that the SF HC-reported charge and payment data be reconciled to the  new PC price and payment data before finalizing expenditure and payment amounts  for the public use file.    Return to Top Consistency  Edits  As discussed above, imputations of PC data to HC drug  mentions that were not exactly matched to PC drug purchases, or refills  (additional acquisitions) thereof, were primarily based on match variables for  the GPI code and the medication name. Additional weighted match variables  included potential third-party payment sources, but these were not required to  be exact-match variables in the imputations because of small cell sizes. As a result, 16,829 HC drug purchases for 1996 had at  least one inconsistent third-party payment source. These were defined as imputed  payments from a given third-party source that was not indicated by the  individual in the HC as a potential payment source. For SFs only, this source  also had to be coded as "not a known payer" in a second set of  variables to be classified as "inconsistent." For the 16,829 drug purchases with inconsistent imputed  payment sources, a hot deck was run in which the 148,644 purchases in 1996 with  consistent payments were used as the donor group for the hot deck. The class  variables selected for the hot deck were the primary payer and the price  category for the drug purchase. The primary payer was determined for the  recipient group according to potential payment sources in the following  hierarchical order: Medicare; private insurance; CHAMPUS; Medicaid; VA; other  Federal; State and local; other; Workers Compensation; out of pocket or  self-payment. The same order was applied to donors, although in their case, the  order referred to actual payments from a source rather than variables indicating  potential payment sources. Then six categories of the primary payer variable  were constructed as the class variable for the hot deck: private; Medicaid;  Medicare; other public (CHAMPUS, VA, other Federal, State and local, and Workers  Compensation); other; and self or family. The price category was divided into  four categories: greater than zero and up to $15; $15.01 up to $30.00; $30.01 up  to $100.00; and over $100.00. Sort variables for the hot deck consisted of six  variables indicating whether each  of the six categories of the primary  payer variable was a consistent payment source. The hot deck imputed percentage shares to each recipient  drug purchase. The percentage shares came from each of the six payment source  categories from the donor record. They were used to allocate the drug price of  the recipient drug to each source. If the "other public" share from a  donor was non-zero and only one of the five sources in this group was a  consistent source, then the full share was allocated to that source. If more  than one of the five sources in the "other public" category was a  consistent source, then the full share was allocated according to the hierarchy  above for choosing among the five sources in this category.    Return to Top The  March 2001 Revision  In the late fall of 2000, records not included on the original public use  version of file HC-010A were identified with missing values of the variable  MEDCYCLE, which indicates the number of times a drug was purchased during a  round. In addition, it was discovered that the value of MEDCYCLE had been  misreported in the survey for certain medications on the original HC-010A file.  A revised public use version of the 1996 prescription drug event file, which  corrected for the missing and misreported MEDCYCLE values, was released in March  2001. This section of the report briefly describes the modifications made to the  previously released public use version of the HC-010A file in May 2000 and the  consequent impacts on the size of the file and on national estimates of  prescription drug utilization and expenditures. To identify misreported MEDCYCLE values, a variable called MEDRATE was  constructed as the days in a round divided by MEDCYCLE. MEDRATE indicates the  maximum value of the average number of days between refills of a prescription  drug within a round for an individual. This estimate is considered to be a  maximum value because it assumes that the person purchased the drug on the first  day of the round. Identifying values of MEDRATE of 3 or less enabled AHRQ staff, in  consultation with a pharmacy expert, to eliminate all of the implausible  MEDCYCLE values. Certain values of MEDCYCLE with values of MEDRATE at or below this threshold  were left intact because a low MEDCYCLE value was combined with a small number  of days in the MEPS round; these were plausible cases, according to the pharmacy  expert. Cases identified as misreported MEDCYCLE values were imputed new values drawn  at random from the distribution of valid MEDCYCLE values for drugs with the same  GPI code. Moreover, as part of the revision to the HC-010A file, all previously  identified free samples were reclassified as purchases because respondents were  not specifically instructed to include counts of free samples in reporting the  survey data that produced the MEDCYCLE variable. Also, a revision was made to  the allocation of Round 3 HC prescription mentions between 1996 and 1997 to  incorporate information regarding the year in which a sampled individual first  started taking the prescription drug (RXBEGYR). With the exception of exactly  matched HC drug mentions, all Round 3 HC drug mentions with MEDCYCLE = 1 and  RXBEGYR = 1996 were allocated to 1996, and all Round 3 HC drug mentions with  RXBEGYR = 1997 were allocated to 1997 regardless of the MEDCYCLE value. All  other Round 3 HC drug acquisitions that were not exact matches but had been  assigned new MEDCYCLE values were allocated to 1996 and 1997 based on the  proportion of time the sampled person was in Round 3 in each year. Any 1996 HC drug acquisitions added to the revised 1996 HC-010A file that had  been omitted from the original file were imputed prescription drug information  from the PC by hot decking to HC drug purchases on both the revised and original  files that had been previously matched to PC drugs. Class variables for the hot  deck included the GPI code for the drug, filer status (SF or NSF), age, sex, and  Medicaid and private drug insurance status. The sort variables included the  remaining insurance status variables, HMO status, and region. The results of the March 2001 revisions to the 1996 file are reported in  Table 3. Of the original 167,784 drug purchases on the file, 26,368 acquisitions  (15.7 percent) were deleted because of misreported MEDCYCLE values. In addition,  4,021 acquisitions with valid MEDCYCLE values (2.4 percent) were reassigned to  1997 because of the revised allocation rules. Another 6,712 acquisitions (4.0  percent) were added to the original file from the newly identified missing  MEDCYCLE cases or were reassigned to 1996 from 1997 because of the new  allocation rules. Finally, another 3,201 previous free samples on the original  file (1.9 percent) became drug purchases in 1996 on the revised file. The March  2001 HC-010A file contains 147,308 drug purchases, representing a net decline of  20,476 purchases, or 12.2 percent, from the original drug file. National estimates of drug purchases declined from 2.116 billion purchases to  1.865 billion purchases, representing a net decline of .251 billion purchases,  or an 11.9-percent reduction. National estimates of prescription drug  expenditures for the civilian noninstitutionalized population in the 1996 MEPS  HC declined from $71.208 billion to $65.291 billion, representing a net decline  of $5.917 billion, or an 8.3- percent decline in national expenditures because  of the modifications made to the file.    Return to Top 
           Table 3 
          Impact of March 2001 file  revision on prescription utilization and expenditures in the 1996 Medical  Expenditure Panel Survey 
              | Category | Acquisitions (unweighted)
 | Weighted acquisitions (billions)
 | Expenditures (billions of dollars)
 |  
              | Original HC-010A file Changes: | 167,784 | 2.116 | $71.208 |  
              | Misreported refills | -26,368 | -.328 | -8.874 |  
              | Reallocated to 1997 | -4,021 | -.049 | -1.443 |  
              | Missing acquisitions | +5,565 | +.069 | +2.381 |  
              | Reallocated to 1996 | +1,147 | +.014 | +.350 |  
              | Free samples | +3,201 | +.042 | +1.659 |  
              | Total net change | -20,476 | -.251 | -5.971 |  
              | Revised HC-010-A file | 147,308 | 1.865 | 65.291 |  Note: Any  differences between components and totals are a result of rounding.  Source: Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality:  Medical Expenditure Panel         Survey, 1996, public use files HC-010A.     Return to Top Reference   Cohen JW, Monheit AC, Beauregard KM, et al. The    Medical Expenditure Panel Survey: a national health information resource. Inquiry 1996;  33:379-89. Appendix A  List of  Abbreviations  AHRQ Agency for Healthcare  Research and Quality            
            AWUP Average wholesale unit  price            
            CFACT Center for Financing, Access, and Cost Trends            
            CHAMPUS Civilian Health and  Medical Program for the Uniformed Services            
            EVNTID Event identification  number            
            GPI Generic Product  Identifier            
            HC Household Component (of  MEPS)            
            HCFA Health Care Financing  Administration            
            HMO Health maintenance  organization            
            MDDB Master Drug Data Base            
            MEDCYCLE The number of times  a prescription drug was purchased during a round            
            MEDRATE The days in a round  divided by MEDCYCLE            
            MEPS Medical Expenditure  Panel Survey            
            MPC Medical Provider  Component (of MEPS)            
            MSA Metropolitan statistical  area            
            NCHS National Center for  Health Statistics            
            NDC National Drug Code            
            NSF Non-self-filer            
            OUT1n Outlier group based on  PRATIOn (= 1 if PRATIOn < .8; = 0 otherwise).            
            OUT2n Outlier group based on  PRATIOn (= 1 if .8 < PRATIOn < 20 for n = 1 and AWUP before 1996 or if  .8 < PRATIOn < 10 otherwise; = 0 else).            
            OUT3n Outlier group based on  PRATIOn (= 1 if PRATIOn > 20 for n = 1 and AWUP before 1996 or if  PRATIOn > 10 otherwise; = 0 else).            
            PC Pharmacy Component (of  MEPS)   
            PERSID Person identification number  PRATIOn The ratio of RUPn to  AWUP, using PRICEn, n = 1,2,3 and dosage amounts to construct RUPn.            
            PRGRP1 One of three groups  used to sort drug events with a positive-valued price for outlier analysis (= 1  if PRICEn = self-payment and PRICEn < $30; = 0 otherwise).            
            PRGRP2 One of three groups  used to sort drug events with a positive-valued price for outlier analysis (= 1  if PRICEn = self-payment and PRICEn > $30; = 0 otherwise).            
            PRGRP3 One of three groups  used to sort drug events with a positive-valued price for outlier analysis (= 1  if PRICEn does not equal self-payment; = 0 otherwise).            
            PRICE1 Measure of the retail  price of the drug product (= the sum of payments when no payments were coded as  missing)  
            PRICE2 Measure of the retail price of the drug  product (= the sum of payments when at least one payment is reported greater  than zero and at least one payment is reported as missing)  PRICE3 Measure of the retail  price of the drug product (= the reported total charge for the drug product when  reported to be greater than zero and all payments are reported to be either  missing or zero)            
            PRICE4 Measure of the retail  price of the drug product (lacked any positive-valued payments or total charge  data)            
            RU Reporting unit            
            RUP Retail unit price            
            SF Self-filer            
            SSS Social and Scientific  Systems, Inc.            
            VA Veterans Affairs              
              Return to Top Appendix B   Pharmacy Component Survey Booklet 
            
              | Pharmacy Component |  
    |  |  
    | 
      
        | PHARID: 
 |  
        | Pharmacy Name: 
 |  
        | Street Address 1: 
 |  
        | City: 
 | State: 
 | Zip: 
 |  |  Return to Top  
            
              |  | DEPARTMENT OF HEALTH &              HUMAN SERVICES |              Public Health Service |  
              | 
 This package is a request for              information about prescription medicines obtained by participants in              the medical Expenditure Panel survey (MEPS). MEPS is a nationwide              study of health care use and expenditures conducted by the Agency              for Health Care Policy and Research (AHCPR) and the National Center              for Health Statistics (NCHS), both part of the U.S. Public Health              Service. On behalf of the Public Health Service and our sponsoring              agencies, we are writing to ask for your cooperation in this              important study. The goal of the study is to              provide government policymakers and private researchers with              accurate information about the rapidly changing health care              situation in this country. To accomplish this, we have collected              information from a cross section of American households on how they              used and paid for health care services and products - including              prescription medicines - during 1996. With the permission of these              households, we are now contacting the pharmacies from which they              reported obtaining prescription medicines during 1996 to obtain              additional information about these medications. One or more of our              study participants identified your pharmacy as a source of              prescription medicines and gave us permission to request the              information we need from your records. A list of these persons and              copies of their signed permission forms are enclosed. This booklet              provides additional information about the study and about the              specific information we are asking you to provide. This survey is authorized by              section 902(a) of the Public Health Service Act [42 U.S.C4 299a].              Participation is voluntary, but we are depending on you to help us              toward a more complete understanding of the nation's health care.              The patient information we obtain will be used for research purposes              only and will be released publicly only in summary form in which              establishments or individuals cannot be identified. The              confidentiality of patient information is protected by Federal              Statute, Section 903(c) and Section 308(d) of the Public Health              Service Act [42 U S.C. 199a -1(c) and 242m(d)]. This law prohibits              the release outside the sponsoring agencies or their contractors of              information that would permit identification of a patient or              establishment without first obtaining permission from the patient or              establishment who gave the information. Data collection coordinators              from our contractor, Westat, Inc., are available to answer any              questions you may have about this data request. If you have any              questions about the forms or procedures, call Westat, Inc.,              toll-free at 1-800-965-5661. Sincerely, |  
              | John M. Eisenberg, M.D., M.B.A. Administrator
 Agency for Health Care
 Policy and Research
 | Edward J. Sondik, Ph.D. Director
 National Center for Health Statistics
 Centers for Disease Control and Prevention
 |  
              | This survey              is authorized under Section 902(a) of the Public Health Service Act              [42 U.S. C 299a. Public reporting              burden
                    for the collection of information is estimated to average
                    five minutes per patient. Any comments regarding this burden
                    or estimate or any other aspect of this collection of information
                    including suggestions for reducing this burden should be
                    sent to: Reports Clearance office, Attention: PRA, United
                    States Public Health Service, Paperwork Reduction Project
                    (0935-0098), Hubert Humphrey Building, Room 737F, 200 Independence
                    Avenue, SW, Washington, DC 20201. |    
            
              | Medical Expenditure Panel Survey Pharmacy  Component In order to get a        complete picture of health care expenses for the Medical Expenditure Panel  Survey (MEPS), we need information from pharmacies and other suppliers of        prescription medicines about the prescribed medicines the study        respondents have received. The individuals listed on the        Patient List (included in the back pocket of this booklet) have given        permission to contact you for information about prescription medicines        they obtained at this location during 1996. Each patient's name, date of        birth, and gender are provided to help you locate them in your records.        Copies of the signed permission forms are also included in the back pocket        of this booklet. For each patient, we are requesting        information about each prescription filled or refilled by your pharmacy,        at this location only, between January 1, 1996 and December 31, 1996. For        each prescribed medicine, we need: 
                    the date on which the            prescription was filled ;the National Drug Code NDC of the            medicine; the generic or trade name of the            drug ;the strength of the medicine and            quantity dispensed; the total charge for the            prescription; and the identity of each source            that paid and the amount paid by each source. |  Return to Top 
            
              | 
                  
                    | How To Respond |  
                    | Use the enclosedpostage paid              return
 envelope to  mail in
 the requested
 information to Westat.
 | If the requested information              is available to you in computerized records: Please send us              a printout of the patient's 1996 records. The printout should show the name of the person for whom the              prescription was filled, and for each prescription filled, the              requested data items.
 |  
                    | Or fax requested information to the
 attention of
 Maralyn Alpert at
 1-800-867-7801
 | If the requested information is not              available to you in computerized records: Please copy the              information from your records onto the enclosed "Prescription              Information List." One is attached to each patients permission              form. Instructions for completing the Prescription Information List              are included at the end of this booklet.
 |  
                    |  | If you prefer to provide the information              by telephone: Please call              1-800-965-566 1, and a data collection coordinator will be happy to              assist you.
 |  |  Return to Top 
            
              
              
                | Common Questions and Answers about the Pharmacy Component |  
                | Q. What is        the Medical  Expenditure Panel Survey?  A. The Medical Expenditure Panel Survey (MEPS)        is a nationwide study conducted to learn more about the health care        services people use, the charges for those services, and the sources that        pay for them. The study is conducted by the U.S. Public Health Service        through the Agency for Health Care Policy and Research and the National        Center for Health Statistics. Data for the study are collected from a        variety of sources, including: |  
              |  | 
                  
                    a nationally representative sample            of households;                   
                    hospitals, physicians, and other            medical providers;                
                    pharmacies;                
                    employers and other sources of            health insurance; and                
                    nursing homes.                 Because of its scope, MEPS is        the most complete source of data available on health care use and expenses        in the United States. |  
              | Q. How are pharmacies        chosen for this study?  A. Pharmacies and other providers of health        care services and products were named by respondents in the household        survey as places that filled or refilled prescriptions for them during        1996. These household respondents  signed forms authorizing and        requesting their pharmacies to release the information sought by the        study. Records are being requested for a  particular person at your        location.  Q. Why is the participation of pharmacies so        important?  A. We understand that pharmacies
                  are very busy places, balancing the needs of serving patients
                  and running a business. However, your participation is crucial
                  to the success of        this study and to the usability
                  of the data collected. The information that you provide will
                  aid in the evaluation of national policies affecting health
                  care use and expenses in the United States. Billions of dollars are spent each year for        prescription medicines, much  of it paid fully or in part by        third-party sources. Patients who are not responsible for paying the        entire cost of their prescriptions often have difficulty providing        complete information about the total cost  and amounts paid for their        prescriptions. We contact pharmacies to collect details the patients        cannot provide. The information  you supply will supplement that        given by the patient and help us build a more complete picture of health        care expenditures for the patients in our study.  Q. How do I know my answers will be kept        confidential?  A. All data provided by the participating        pharmacies and their patients will be kept in strict confidence. Your        rights to confidentiality are protected by Federal law  under        Sections 903(c) and 308(d) of the Public Health Service Act and the        Privacy Act of 1974. All personal identifying information such as names        or addresses will be removed before information from the study is made        available to researchers. The information you give will be published only        in statistical summaries and tabular format.  Q. Why is a MEPS study needed now?  A. The U.S Public Health Service
                  is committed to improving the nation's health care system.
                  Since this study was last conducted in 1987, many important
                  changes have taken place in: 
                    the way people choose their providers of medical            care,the ways in which health care is paid for, andthe kinds of health insurance plans available and            the services covered by those plans. These and other changes have created  a        critical need for more up-to-date information on the types of health care        services and products people obtain and how these services and products        are paid for. The MEPS study results will inform the public, the health        care community, and leaders in government and the private sector.  Q. Who is conducting the data collection?  A. The U.S. Public Health  Service has        chosen  Westat, a national research company, to collect the pharmacy        data.  |  
            
              | Q. What questions will the study answer?  A. The study will provide answers to many        important questions. For example: |  
              | 
                  How much of health care costs, including            prescriptions and medical services, are covered by insurance?How much do people pay out of pocket for health            care services?What kinds of medications are not covered by most            insurance plans?How many people have no health insurance at all?In what ways does the health care received by            people in cities differ from the care received by people in rural            areas?What health care costs do families and            individuals face?What does a serious illness cost? |  |  
              | Q. Any further questions?  A. If you have any other questions about this        study, please call toll-free at 1-800-965-5661, and a MEPS  survey        representative will be happy to assist you. Many books reports, and articles based on the        information from this survey series have been published and are available        at no cost. If you are interested in seeing a list of the most popular        publications, please call  the 800 number listed above. |  Return to Top   
            
              
                | Pharmacy Component Prescription Information List  Instructions |  
                | Please follow these instructions as you  complete the Prescription Information List. The boxes on the left refer to the  data items of the sample Prescription Information List  on the facing page. |  
              | DATE FILLED | Record the date the prescription was        filled or refilled. |  
              | NDC | Record the National Drug Code        (NDC) for the medicine received. This is usually an 11-digit number        (5-4-2) that is assigned to the specific medicine. For example:        00173-0428-00 for Zantac 150 GELdose Capsules in a bottle of 60. |  
              | GENERIC/ TRADE
 NAME(S)
 | Record  the generic        (also, nonproprietary
                or product) name and / or the trade (also, manufacturer, proprietary,
                or brand) name of the medicine. (Generic Name: The "common"  or chemical name a        pharmaceutical product is manufactured and sold under. Many but not all        medications have a generic equivalent.)
 (Brand Name: The name applied by a manufacturer to a particular        medication. Sometimes brand names are more familiar than the generic        name.)
 (Manufacturer Name: Refers to the company that produces or sells        the medicine.)
 |  
              | STRENGTH | For the strength of the medicine , record        both, the amount and the unit (e.g., mg, gm, gr, mEg, mcg, %,         ml). |  
              | QUANTITY (package size/
 amount dispensed)
 | Record the amount of medicine dispensed       
                to the patient (e.g., 20 pills, 4 fl. oz., etc.). |  
              | TOTAL CHARGE
 | Record the dollar amount of the total        charge. This is the price of the prescription: the cash price if it is a        cash transaction, or the contract price if it is a third-party        transaction. The prescription price is calculated based on the specific        prescription and / or  the specific payor's contracted reimbursement        rate. |  
              | PAYMENTS | 
                  Patient Payment: Record the total            dollar amount of the payment made by the patient. Include any payments            made to meet the patient's copayment, coinsurance or deductible.Private Insurance Payment: Record            the total dollar amount of all payments, if any, made by private            health insurance sources. Private insurance sources do include            insurance that is paid by an employer or an individual. Do not include            payments made by public insurance sources, such as Medicaid, Medicare,            etc. Those should be included under "Medicaid",            "Veteran's Administration", "CHAMPUS/CHAMPVA",            "Other Federal", "Other State",             "Workers Compensation", or "Other" as appropriate.Medicaid Payment: Record the total            dollar amount of the payment made by Medicaid, if any.Veteran's Administration Payment: Record the total dollar amount of the payment made by Veteran's            Administration, if any.CHAMPUS/CHAMPVA Payment: Record the            total dollar amount of the payment made by CHAMPUS/CHAMPVA if any.Other Federal Payment: Record the            total dollar amount of the payment made by Other Federal sources, if            any.Other State Payment:  Record            the total dollar amount of the payment made by Other State sources, if            any.Worker's Compensation Payment: Record the total dollar amount of the payment made by Worker's            compensation, if any.Other Payment: Record the total            dollar amount of the payment made by other sources, if any. |  
              | If you have questions about how to complete these forms or all the requested data items are not        available at your location, please call a data collection coordinator at        this toll-free number: 1-800-965-5661. |  Return to Top Sample Prescription Information  List Medical Expenditure Panel Survey - U.S. Public Health Service
 
            
              | 
                  
                    | SANDIE  M KING DOB: 07/10/65  * FEMALE
 42816659-666123B5253
 WALGREEN'S PHARMACY63335109
 |  | 
                  
                    | For the patient listed to the left, please provide information about  each              prescription filled or refilled  between January 1, 1996              and  December 31, 1996. 
 |  |    
            
              | 
                  
                    | 1. | Date Filled: 03/26/96 |  
                    |  | NDC: 00003-0109-60 |  
                    |  | Generic/Trade Name(s): Amoxicillin              (BMS) |  
                    |  | Strength: 500         unit: mg |  
                    |  | Quantity (Pkg. Size/Amt.Dispensed): 21 |  
                    |  | Total Charge1:              $ 7.00 |  | 
                  
                    | Payments: |  
                    |  | Patient2:              $ 6.00 | Other Federal: $ |  
                    |  | Private Ins3.:              $ 1.00 | Other Sate: $ |  
                    |  | Medicaid: $ | Worker's Comp: $ |  
                    |  | VA: $ | Other: $ |  
                    |  | CHAMPUS/CHAMPVA: $ |  |  
              | 
                  
                    | 2. | Date Filled: 03/24/96 |  
                    |  | NDC: 00085-0647-03 |  
                    |  | Generic/Trade Name(s): Intro              -A  Inj |  
                    |  | Strength: 3         unit: mmu/vial |  
                    |  | Quantity (Pkg. Size/Amt.Dispensed): 12 |  
                    |  | Total Charge1:              $ 370.09 |  | 
                  
                    | Payments: |  
                    |  | Patient: $ 18.00 | Other Federal: $ |  
                    |  | Private Ins.: $ 352.09 | Other Sate: $ |  
                    |  | Medicaid: $ | Worker's Comp: $ |  
                    |  | VA: $ | Other: $ |  
                    |  | CHAMPUS/CHAMPVA: $ |  |  
              | 
                  
                    | 3. | Date Filled: |  
                    |  | NDC: |  
                    |  | Generic/Trade Name(s): |  
                    |  | Strength:          unit: |  
                    |  | Quantity (Pkg. Size/Amt.Dispensed): |  
                    |  | Total Charge1:              $ |  | 
                  
                    | Payments: |  
                    |  | Patient:              $ | Other Federal: $ |  
                    |  | Private Ins.: $ | Other Sate: $ |  
                    |  | Medicaid: $ | Worker's Comp: $ |  
                    |  | VA: $ | Other: $ |  
                    |  | CHAMPUS/CHAMPVA: $ |  |   1 Total charge: Record the  dollar amount of the total charge. This is the price of the prescription: the  cash price if it is a cash transaction, or the contract price if it is a third  party transaction. The prescription price is calculated based on the specific  prescription and/or the specific payor's contracted reimbursement rate.  2 Patient Payment. Record  the total dollar amount of the payment made by the patient. Include any payments  made to meet the patient's copayment, coinsurance, or deductible.  3 Private Insurance  Payment. Record the total dollar amount of all payments, if any, made by private  health insurance sources. Private insurance sources do include insurance that is  paid by an employer or an individual. Do not include payments made by public  insurance sources, such as Medicaid, Medicare, VA, etc. Those should be included  under "Medicaid," "Veterans' Administration," 'CHAMPUS/  CHAMPVA," 'Other Federal," 'Other State," 'Workers'  Compensation," or "Other," as appropriate.   You may respond to this request by any of  the following methods: 
            Mail the requested information in the      postage paid envelope.Fax the requested information to the      attention of Maralyn Alpert at 1-800-867-7801.Provide the requested information over      the phone by calling 1-800-965-5661.  Thank you for your participation! If you have any questions or concerns  after you have returned the requested information, please call Maralyn Alpert at  1-800-965-5661. Westat 1650 Research Blvd, Rockville, MD  20850    Return to Top Appendix C Permission Form for Pharmacy Component    
            
              
                | OMB #: 0935-0098 |  
                | PERMISSION FORM   MEDICAL EXPENDITURE PANEL        SURVEY - U.S. Public Health Service
 AUTHORIZATION TO OBTAIN INFORMATION FROM PHARMACIES AND PHARMACY RECORDS
 |  
              | A. TO: Pharmacy:
 
 |  
              | Street Address 1: 
 |  
              | Street Address 2: 
 |  
              | City: 
 | State: 
 | Zip: 
 |  
              | Telephone: 
 |  |  |  
              | B.  I am              voluntarily participating in this survey of health care use and              expenses in the USA, a part of the Medical Expenditure Panel Survey              being conducted by the United States Public Health Service. By this              statement or a photocopy of it, I hereby authorize and request you              to supply any needed medical or billing information about prescribed              medicines filled or refilled for my use during the period January              1, 1996 to December 31, 1996. This request applies to any and              all prescribed medications received by me during this period.
 I understand that the Public              Health Service will use the information for statistical purposes in              health research, and that no information which identifies me or my              pharmaceutical providers will ever be released or published.              Information about me from the survey interview may be used to              identify my records as necessary. This request expires 18 months              from the date of signature, unless I inform you otherwise. 
 |  
              | 
                  
                    | C. 1.  Patient's Name
 
 |  
                    | 2. Date Of Birth Month/Day/Year
 
 | 3. Other Names Under            Which Records May be Filled
 
 |  
                    | 3A. Social Security Number 
 
 
 |  |  |  
    | 
 |  
    | D. |  
    | 4. Patient's Signature - 14 and over sign 
 
 | 5. Date      Signed 
 
 |  
    | 
 |  
    | E. |  
    | 6. Parent, Guardian,  Witness or Proxy's    Signature
 
 | 7. Date      Signed 
 |  
    | 8.   Signer's Relationship to Patient
 
 |  |  
    | 9. Reason for      Parent, Guardian, Witness or Proxy's Signanture: 
          Patient 13 or YoungerPatient 14-17 Years OldPatient DeceasedPatient DisabledPatient In Health Care Institution |  
    | *NOTICE: Information contained on this form that would permit identification of          any individual or establishment has been collected with a promise that          it will be held in strict confidence by the sponsoring agencies or their          contractors, will be used only for purposes stated in this study, and          will not be disclosed or released to anyone other than authorized staff          of the sponsoring agencies, AHCPR and NCHS, without the consent of the          individual or the establishment in accordance with Section 903(c) and          Section 308(d) of the Public Health Service Act [42 U.S.C. 299a-1(c) and          242m(d)]. No information will be disclosed where prohibited by federal          law and regulations governing the confidentiality of alcohol and drug          abuse patient records, 42 USC 290dd-3 and 290cc-3, 42 CFR Part 2.  **NOTICE: Your          Social Security Number is requested to allow the addressee to accurately          identify and locate your records. This information is voluntary and is          collected under the authority of Title IX, Section 902(a) of the Public          Health Services Act (42 U.S.C. 299a). There will be no effect on your          benefits and no information will be given to any other government or          nongovernment agency. |  Source:  Center for Financing, Access, and Cost Trends, Agency for Healthcare Research and Quality.
            Return to Top 
            
              |  Suggested Citation:Moeller, J. F., Stagnitti, M. N., Horan, E., Ward, Kieffer, N., Hock, E. Methodology Report #12:  
                Outpatient Prescription Drugs: Data Collection and Editing in the 1996 MEPS (HC-010A). June 2001. Agency for Healthcare Research and Quality, Rockville, MD.
                http://www.meps.ahrq.gov/data_files/publications/mr12/mr12.shtml
 |  |